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Educational Articles

Small Mammals + Surgical Conditions

  • An ovariohysterectomy is often referred to as a spay or spaying. It is a surgical procedure in which the left and right ovary and both left and right horns of the uterus are removed completely, to sterilize or render a female animal infertile. Spaying minimizes the risk of ovarian, uterine, breast, and pituitary gland cancers in rats. Ideally, most rats are spayed between four and six months of age. Complications are rare, but there is a small risk associated with being anesthetized. Most rats will experience no adverse effects and spaying is generally recommended for all healthy, young rats to prevent future health problems.

  • Malignant lymphoma (lymphosarcoma) and leukemia are among the most common malignancies seen in ferrets. Diagnosis may be made by fine needle aspiration or biopsy. For a dedicated owner with a compliant patient, surgery and/or treatment with chemotherapy is an option. Remission of lymphoma is possible with treatment in ferrets, but recurrence is common. Ferrets also commonly develop insulin-producing tumors of the pancreas that lower the ferret’s blood sugar and cause weakness, weight loss, lethargy, seizures, coma, and death. Insulinoma commonly spreads from the pancreas to the liver, so surgical removal of pancreatic insulinoma nodules may not be curative. Affected ferrets respond well for months to years to medical therapy with glucose-promoting drugs (prednisone) and anti-insulin drugs (diazoxide). Drugs suppress effects of the tumor but do not eliminate it; and ferrets on medical treatment must have their medications increased over time as the tumor grows.