Educational Articles
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This handout discusses meningitis, an inflammation of the membranes that cover the brain and spinal cord, in dogs. The numerous potential causes, along with the diagnosis, treatment and prognosis of the condition are outlined.
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Meningoencephalitis is a term referring to inflammation of the brain and the surrounding fluid and tissues. Meningoencephalitis of unknown origin is a term used to describe those cases of meningoencephalitis in which MRI and cerebrospinal fluid analysis indicate the disease but diagnosis through histopathological analysis is not possible. Treatment typically involves immunosuppressant drugs, sometimes with the addition of antibiotics. The prognosis depends on several factors, which are also explained in this handout.
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Metaldehyde toxicity occurs when a dog (or a cat, less commonly) eats slug bait that contains metaldehyde. Signs of metaldehyde toxicity include vomiting, anxiety, ataxia (due to muscle incoordination), stiffness, muscle tremors, elevated heart rate and respiratory rate, increased salivation, and increased sensitivity to touch. These signs often progress to continuous muscle tremors and seizures. Prognosis is good with aggressive treatment.
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Methazolamide (brand names Neptazane®, GlaucTabs®, Glaumetax®, MZM) is a carbonic anhydrase inhibitor used off label (extra label) to treat open angle glaucoma in dogs and cats. Do not use in pets that are allergic to it, have significant liver, kidney, or adrenal disease, have electrolyte imbalances, have severe obstructive lung disease, or have closed angle glaucoma.
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Methionine (brand name Methio-Form) is a nutritional supplement used to make urine more acidic in cats and dogs. Urine acidifiers help manage certain types of urolithiasis (urinary stones). Methionine comes in gel, chewable, powder, and tablet forms. Monitor urine pH and seek immediate veterinary care if signs of Heinz-body anemia appear in cats (pale gums, red-brown urine, weakness).
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Metoprolol is a beta-blocker used to treat certain heart rhythm problems and hypertension (high blood pressure) in cats and dogs. It has also been used in the treatment of hypertrophic cardiomyopathy (HCM) in cats. It is used off label (extra label) in veterinary medicine.
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Mexiletine is given by mouth and is used off label to treat abnormal heart rhythms and muscle disorders in dogs. Common side effects include stomach upset such as vomiting, trembling, or dizziness. Do not use in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.
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Miconazole + chlorhexidine + tris-EDTA topical (brand name MiconaHex+Triz®) is an antifungal and antimicrobial cleansing agent used in the treatment of surface skin infections and to enhance the effectiveness of other topical antibiotics in cats and dogs. It comes in spray, mousse, shampoo, and wipe forms.
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Miconazole otic is an antifungal used in the treatment of external ear infections (otitis externa) caused by fungal organisms in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. Miconazole otic comes in ointment or liquid drop suspension forms that may be specially compounded.
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Miconazole topical is an antifungal used in the treatment of skin infections caused by yeast in cats and dogs. It may be used “off-label” or “extra label” for other conditions and in other animals. It may be specially compounded and/or combined into a formulation with other medications. Miconazole topical comes in a variety of forms.