Educational Articles
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The Ebola virus is very contagious and is transmitted through blood, body fluids, and tissues, but not through air, water, or food. Ebola affects humans, non-human primates, and is carried by fruit bats. Other species do not appear to be affected, although there has been evidence of exposure to the disease in dogs, cats, and other domestic animals. Domestic animals are not believed to transmit the virus; however, there is a risk that they could transmit body fluids such as saliva on their fur to other humans. Any potential exposure to Ebola should be reported to your veterinarian who will contact the Center for Disease Control (CDC).
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Pheromones (brand names Feliway®, Comfort Zone®, Adaptil®, others) are natural or synthetic substances that mimic scents released by animals to communicate. Pheromones are used in cats and dogs as behavior modifiers for a variety of conditions, including urine spraying and marking, inter-cat aggression, stressful events, phobias, and separation anxiety, among other conditions. Pheromones comes in collar, diffuser, and spray forms.
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Phytosphingosine topical (brand names Douxo®, SkinGuard®) is an anti-inflammatory agent, with antibacterial and antifungal properties. It is used in cats and dogs to help relieve itching in certain skin conditions and help restore the skin barrier. Phytosphingosine topical may be part of a combination product.
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Pigmentary keratitis is a discoloration of the cornea due to chronic inflammation and is most common in brachycephalic breeds. In many cases, complete resolution cannot be achieved, but the condition can be stopped or slowed down if the underlying cause can be identified and treated. Surgery and medications may be used to help address the problem.
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Pilocarpine is used off-label and given by mouth in food to treat neurogenic keratoconjunctivitis sicca, and used topically in the eye to diagnose cranial nerve III problems. Common side effects include irritation of the eye, and more severe side effects include vomiting, diarrhea, increased salivation and urination, and coughing. Do not use in pets that are allergic to it or that have secondary glaucoma.
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Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The most common functional pituitary macroadenoma in the dog secretes the hormone ACTH, causing increased cortisol levels and Cushing’s disease. Non-functional macroadenomas cause clinical signs through compression of nearby structures resulting in vision changes, diabetes insipidus, and neurologic disorders. This handout explains the effects of these tumors on dogs, how they are diagnosed, and the treatment options available.
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Platelet-rich plasma or PRP is a form of regenerative medicine where the platelet and protein components of blood are retrieved from a patient and then injected back into the patient at the site of inflammation. PRP contains growth factors that appear to promote tissue regeneration and reduce inflammation. The procedure is not yet widely available and should only be performed by a veterinarian with specialized equipment and special training in this area.
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Pleural effusion refers to the abnormal accumulation of fluid within the chest cavity. The fluid is not found within the lungs, but instead within the pleural sac, essentially meaning the lungs are floating in a chest that is full of fluid. There are several causes, including chylothorax, heart failure, and lung or chest tumors. Dogs presenting for pleural effusion are often experiencing shortness of breath and decreased oxygen intake; placing them into an oxygen cage provides some degree of immediate relief. Removing the fluid that surrounds the lungs will allow the dog to breathe more readily and this fluid can then be tested to identify the cause of the pleural effusion. The treatment and prognosis vary depending on the underlying cause.
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Pneumothorax is an accumulation of air outside the lungs, but inside the chest wall. The air outside the lung prevents the lungs from inflating normally, and can lead to lung collapse. There are several variations of pneumothorax.
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Polycystic kidney disease (PKD) is an inherited kidney disease that is common in cats, but uncommon in dogs. Dogs with polycystic kidney disease develop multiple fluid-filled cysts within the kidney, with the number and size of these cysts increasing with age. As the kidney cysts displace larger amounts of functioning kidney tissue, the dog begins to show signs of chronic kidney disease. There is no specific treatment for polycystic kidney disease; treatment is centered on alleviating the signs of chronic kidney disease.