Educational Articles
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Chemotherapy is the therapeutic use of chemical agents to destroy or inhibit the growth and division of cancer cells. Usually, chemotherapy is used when tumors are widespread or when there is significant or immediate risk of spread from the primary location. It is often used following the surgical removal of tumors. In some cases, chemotherapy is started prior to surgery. The side effects of chemotherapy are related to the effects of chemotherapy on normal -as well as cancerous- cells. The principal goal of cancer care in pets is to provide cancer control without reducing quality of life.
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Chondrosarcomas arise from cartilage, which is a connective tissue primarily found where bones meet with joints, as well as at other locations in the body such as the nasal cavity, and ribs. Chondrosarcoma is the second-most common primary bone tumor in dogs. Canine chondrosarcoma most commonly affects the flat bones of the body, such as the ribs, skull, nasal cavity, and pelvis, although the limbs can also be affected. Aggressive surgical removal is typically recommended, although radiation therapy may also be used, depending on location of tumor. Metastasis may occur but is relatively uncommon.
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Cornifying epitheliomas are benign skin tumors that are secondary to keratin buildup. They can develop anywhere but may be most troubling if they affect the skin around the nail, causing swelling, discomfort, and lameness. Surgical removal is curative in most cases.
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Lymphoma is a type of cancer that is common in dogs. When it occurs in the skin, it is called cutaneous lymphoma, but this form is quite rare. Canine cutaneous lymphoma can present various clinical signs, including itching, alopecia (hair loss), scaly skin, skin redness, loss of skin color, ulcers, nodules, pustules, and plaques.
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Collecting tissue samples for cytology or histopathology allow a pathologist to often give a diagnosis of the type of mass or tumor your pet has. Samples can be obtained by fine needle aspirate or biopsy, where a piece of the mass is cut out. Based on what the mass appears like under the microscope, the pathologist can often give a prognosis of how the tumor will behave.
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Esophageal tumors are extremely rare but more often than not malignant type tumors. The cause is unknown but cases in tropical environments may be due to infection by the worm Spirocerca lupi. Treatment options are limited as surgical complications are high due to the advanced nature of the disease at time of diagnosis.
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Hepatoid gland tumors are a type of cancer that develops from the sebaceous (sweat) glands of the skin. They most commonly develop in the perianal area. Perianal adenocarcinomas, and rarely perianal epitheliomas may also occur. These tumors appear as one or more small, round, pink, hairless, slow-growing nodules around the anus, and can sometimes ulcerate and become infected. Diagnosis, treatment, and prognosis are discussed.
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Infertility in a female dog is defined as the inability to conceive and deliver viable puppies, even when mated multiple times with a known fertile male surrounding the time of ovulation. This handout outlines the varying causes of infertility in female dogs and how they may be diagnosed and treated.
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Intestinal tumors are uncommon in dogs and cats, comprising about 2% of all cancers. There are many kinds, including leiomyosarcomas, lymphomas, adenocarcinomas, mast cell tumors, gastrointestinal stromal tumors (GISTs), plasmacytomas, carcinoids, and osteosarcomas (all malignant) and leiomyomas, adenomatous polyps, and adenomas (all benign). Most intestinal tumors are malignant. Intestinal tumors are more prevalent in older animals and certain breeds. Signs, diagnosis, and treatment are discussed.
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Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.