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Educational Articles

Medications & Supplements

  • Sildenafil is given by mouth or injection and is used off label to treat high blood pressure in the lungs or to treat megaesophagus. Give as directed. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, or skin redness in the groin area. Do not use in pets that are allergic to it or pets that take nitrate medications. If a negative reaction occurs, please call your veterinarian.

  • Silver sulfadiazine topical is an antimicrobial used to treat skin infections and burns in cats, dogs, and exotic pets. It is used off label in veterinary medicine. Silver sulfadiazine topical comes in a topical cream.

  • Sodium chloride (hypertonic) ophthalmic is a topical medication used to reduce surface (corneal) swelling of the eye in cats and dogs. Sodium chloride is available without a prescription but should only be used under the direction of a veterinarian. It may be used “off label” or “extra label” to treat eye conditions in animals other than cats or dogs. Sodium chloride (hypertonic) ophthalmic comes in ointment and liquid drop form. Avoid use in animals with corneal ulceration or dry eye.

  • Spinetoram topical (brand name Cheristin®) is an insecticide used to prevent and treat flea infestations in cats and kittens. Avoid use in dogs. It comes in a liquid drop form.

  • Spinosad (brand name Comfortis®) is an antiparasitic used to kill adult fleas and to prevent and treat flea infestations in dogs and cats. It may be used off label (extra label) to treat other parasites and in other animals. It comes in an oral tablet form.

  • Spironolactone + benazepril (brand name Cardalis®) is a combination aldosterone antagonist (spironolactone) and angiotensin-converting enzyme inhibitor or ACE inhibitor (benazepril) used to treat certain types of congestive heart failure in dogs. Use to treat other heart conditions or in other species is "off label" or "extra label". Spironolactone + benazepril comes in chewable meat-flavored tablet form.

  • Spironolactone + hydrochlorothiazide is a combination aldosterone antagonist (spironolactone) and thiazide diuretic (hydrochlorothiazide) used to remove excess fluid and salt from the body in cats and dogs. This medication can be used in combination with other drugs to lower blood pressure and for protective effects on the heart muscle. It has also been used in dogs with fluid-up in the abdomen due to liver failure.

  • Sulfadiazine/trimethoprim is given by mouth in the form of a liquid suspension or is given by injection in the hospital. It is commonly used to treat bacterial and parasitic infections, sometimes off label, in dogs, cats, small mammals and other exotics. Common side effects include a decreased appetite, vomiting, and diarrhea, although more serious side effects are possible, such as dry eye, or liver, blood, or urinary problems. Do not use in pets that have severe liver damage, blood cell problems, dehydration, or sulfa allergies. If a negative reaction occurs, please call your veterinary office.

  • Sulfadimethoxine is an antimicrobial given by mouth in the form of a tablet or liquid suspension, used primarily to treat coccidiosis. Its use for treating small mammals and reptiles is off label. Common side effects include vomiting, diarrhea, and decreased appetite. This medication should not be used in pets that are allergic to it, pregnant, lactating, or have severe liver or kidney dysfunction. If a negative reaction occurs, call your veterinary office.

  • Sulfur, precipitated, topical (brand name Sulfodene®, others), is a medication used in the treatment of seborrheic (dry or greasy dandruff) disorders in cats and dogs to dissolve skin flakes and scales. It can have antibacterial, antifungal, and antiparasitic effects. It may be specially compounded and/or combined into a formulation with other medications.