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Educational Articles

Medications & Supplements

  • Diphenhydramine topical (brand name Benasoothe®) is an antihistamine with some local anesthetic properties. It is used to relieve itching and skin irritation in dogs, cats, and other animals. Diphenhydramine topical comes in a variety of forms, which may be specially compounded.

  • Diphenoxylate + atropine (brand name Lomotil) is an opioid combination medication used to treat diarrhea or coughing in dogs and diarrhea in cats. Its use in cats is not generally recommended. Diphenoxylate + atropine is given by mouth in the form of a tablet or liquid. This article discusses administration, potential side effects, risks, and monitoring.

  • Ear cleansing/drying products are used over-the-counter to treat and prevent ear infections in many species of pets. They come as a liquid solution that is used topically within the ear canal and are typically used in the ears after debris and wax have been removed using a cerumenolytic cleanser.

  • Emodepside/praziquantel (brand name Profender®), is an antiparasitic drug used to treat and control hookworms, roundworms, and tapeworms in cats. Empodepside with praziquantel comes in topical solution form that is applied directly to the skin.

  • Enilconazole is a topical wash/dip used to treat dermatophytosis (ring worm) in dogs and sometimes in cats. Side effects are uncommon as it is relatively well-tolerated, but in cats may include drooling, vomiting, lack of appetite, weight loss, muscle weakness, and elevated liver enzymes. Do not use in cats unless directed by your veterinarian. If a negative reaction occurs, please call your veterinary office.

  • Enrofloxacin otic is applied topically and is labeled to treat ear infections in dogs. It is also used off-label to treat ear infections in cats. Give as directed. Side effects are rare but may include temporary hearing loss or skin reactions. Do not use with pets allergic to quinolones or sulfonamides, with young animals, or with those with central nervous system disorders. If a negative reaction occurs, please call the veterinary office.

  • Enzymatic toothpaste (brand name C.E.T., others) is a product used at home by pet owners to aid in tooth brushing that minimizes plaque and tartar formation on the exterior of the tooth (the crown), and also assists in the maintenance of good oral hygiene. It can be used on both dogs and cats.

  • Epineprhine is a drug used most often in emergency situations for animals (e.g., anaphylaxis, cardiopulmonary resuscitation/CPR). It may be added to local anesthesia drugs due to its ability to cause veins to constrict, thus delaying the body’s absorption of the drugs and prolonging the duration of the local anesthetic duration.

  • Eprinomectin + praziquantel (brand name Centragard®) is a topical (spot-on) antiparasitic drug used to treat and control hookworm, roundworm, and tapeworm infections, and to prevent heartworm disease in cats and kittens that are at least 7 weeks of age and weigh at least 0.8 kg (1.8 lb). Do not use in cats known or suspected to have two copies of the MDR1 gene mutation.

  • Erythromycin is given by mouth or injection and is used off label to treat bacterial infections and gastrointestinal motility problems in many animal species. Common side effects include diarrhea, lack of appetite, and vomiting. Do not use in pets that are allergic to it, have liver disease or dysfunction, or in pets such as rabbits, gerbils, guinea pigs, or hamsters. If a negative reaction occurs, please call your veterinary office.